DEVICES AND METHODS FOR MAGNETIC ISOLATION AND ANALYSIS OF RARE CELLS

Unmet Need
Numerous devices and methods have been developed to try and isolate circulating tumor cells in a reproducible and efficient manner. To date, the majority of work has been performed utilizing the CellSearch test, which is the only FDA-approved device. However, the CellSearch test is limited by the associated expense and not being able to be used at point-of-care (POC). A POC, easy to use device is still needed in the cancer field.


Technology Overview
The closest “Lab on a Chip” cell isolation device with Immiscible Filtration Assisted by Surface Tension (IFAST), has been reported from the University of Wisconsin-Madison [6-9]. The method of using a magnetic field to displace the PMP and surface tension to separate the cells from the solution is the same in out ST device. However, the construction of our device is novel, with several differences that may have potential advantages.

Stage of Development
Prototype

Publications
N/A
 

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