Geometric Calibration for Cone Beam CT using Line Fiducials

Case ID:
C14316
Disclosure Date:
8/5/2016
Description:
Unmet Need
Traditional BB-based geometric calibration methods for cone-beam CT (CBCT) rely significantly on foreknowledge of the scan trajectory shape. This is a hindrance to the implementation of variable trajectory CBCT systems, normally requiring a dedicated calibration phantom or algorithm for every scan orbit of interest. A more flexible method of calibration is proposed here that accommodates various orbit types – including strongly noncircular trajectories – without software or phantom redesign.

Technical Details
The proposed method uses a calibration phantom consisting of multiple radio-opaque wire segments. Geometric models relating the 3D line equations of the wires to the 2D line equations of their projections are used as the basis for system geometry estimation. This method was tested using a mobile C-arm CT system and comparisons were made to standard BB-based calibrations. Simulation studies were also conducted using a sinusoid-on-sphere orbit. Calibration performance was quantified in terms of PSF and back projection error, and visual image quality was assessed with respect to spatial resolution in trabecular bone in an anthropomorphic head phantom.  The line fiducial calibration method performed equal to or better than BB-based calibrations in all metrics. For the sinusoidal scans, the method provided reliable calibration, validating its application to non-circular trajectories. Furthermore, the ability to improve image quality using non-circular orbits in conjunction with this calibration method was demonstrated.  The proposed method has been shown feasible for conventional circular CBCT scans and offers a promising tool for non-circular scan orbits that can improve image quality, reduce dose, and extend field of view.

Stage of Development
Pre-clinical

Publication(s)
"Geometric Calibration Using Line Fiducials for Cone-Beam CT with General, Non-Circular Source-Detector Trajectories"


 
Patent Information:
Title App Type Country Serial No. Patent No. File Date Issued Date Expire Date Patent Status
Geometric Calibration for Cone Beam CT using Line Fiducials PCT: Patent Cooperation Treaty PCT PCT/US2018/022809   3/16/2018     Pending
Inventors:
Category(s):
For Information, Contact:
Mitchell Harris
mharr145@jhu.edu
410-614-0300
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