Mini-cancers Utilization as Decision Tools for Personalized Cancer Drug Regimens

Case ID:
C14489
Disclosure Date:
12/2/2016
Description:
The present invention includes methods for identifying chemotherapy treatments specifically suited for each cancer patient. The methods include obtaining a biopsy from the cancer patient; establishing a cancer culture from the biopsy; mixing the cancer culture with a matrix forming mini cancers.  The mini cancers are then used to screen chemotherapy agents by identifying those agents that completely stop mini cancer growth, inhibit mini cancer growth, and/or  inhibit invasion of the mini cancers in a surrounding extracellular matrix. Since the mini cancers are derived from the patient, only the most effective chemotherapy agent(s) will be chosen to  treat the cancer patient; minimizing the length of chemotherapy treatment, the cost of such treatments, and patient related illness. 
Patent Information:
Title App Type Country Serial No. Patent No. File Date Issued Date Expire Date Patent Status
Mini-cancers Utilization as Decision Tools for Personalized Cancer Drug Regimens PRO: Provisional United States 62/454,133 2/3/2017     Expired
Mini-cancers Utilization as Decision Tools for Personalized Cancer Drug Regimens PCT: Patent Cooperation Treaty PCT PCT/US2018/016356   1/2/2018     Pending
Inventors:
Category(s):
For Information, Contact:
Jon Gottlieb
jgottl10@jhu.edu
410-614-0300
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