An Eye Drop Technology with Enhanced Hyaluronic Acid Retention and Delivery to Ocular Tissues

Case ID:
C13662
Disclosure Date:
6/1/2015
Description:
The present invention provides biomaterial compositions that can immobilize HA to the ocular surfaces through an HABpep and transmembrane mucins and collagen of ocular tissues can act as anchoring sites. These biomaterial compositions provide prolonged HA binding and retention in both ex vivo and in vivo animal models. HA eye drop solutions with these the inventive biomaterials can prolong the biological and physical benefits to the ocular surface and potentially be more effective in treating eye disorders including dry eye than standard HA-eye drop presently available. Methods of making and use of the compositions are also provided.
Published Material: WO/2017/031146
Patent Information:
Title App Type Country Serial No. Patent No. File Date Issued Date Expire Date Patent Status
An Eye Drop Technology with Enhanced Hyaluronic Acid Retention and Delivery to Ocular Tissues PCT: Patent Cooperation Treaty United States 15/753,674 2/20/2018     Pending
Inventors:
Category(s):
For Information, Contact:
Mitchell Harris
mharr145@jhu.edu
410-614-0300
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