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RF Ablation Lesion Assessment System
Case ID:
C13726
Disclosure Date:
1/8/2016
Web Published:
4/20/2017
Unmet Need:
Catheter-based cardiac Radio frequency (RF) ablation has become a common treatment for arrhythmias such as atrial fibrillation or ventricular tachycardia. Cardiac ablation requires contiguous transmural lesions to be made between anatomical boundaries. Incomplete ablations are thought to result in a 40-50% recurrence rate in patients undergoing cardiac ablation for treatment of atrial fibrillation. Currently, assessment of lesion effectiveness is conducted by indirect measures. Real-time assessment of tissue depth and transmural lesion formation would allow the operator to adjust ablation parameters to safely deliver and confirm transmural lesions. JHU inventor has created a device which includes an electrode-antenna and method for real-time detection of ablated and non-ablated tissue.
Technical Details:
JHU inventor has an RF Ablation Lesion Assessment System which works in the current EP catheter lab settings. The detectable changes between ablated and non-ablated tissue should provide sufficient dielectric contrast to distinguish tissue types and extent of ablation by monitoring time-domain reflection coefficient peaks of the electrode-antenna. Since the measurements are carried out in a wide frequency range, ablated tissue thickness will influence electrical properties characteristics of the electrode-antenna. The System includes an innovative catheter with integrated high-frequency sensing and RF ablation (HFS-RFA) to enable assessing lesion formation during ablation with a single catheter.. The System includes a user interface for easy analysis of the changes in tissue electrical properties and display the progression and rate of lesion formation.
Stage of development/data:
Proof-of-concept
ex vivo
bench-top experiment
Patent Information:
Title
App Type
Country
Serial No.
Patent No.
File Date
Issued Date
Expire Date
Patent Status
TISSUE ABLATION AND ASSESSMENT SYSTEM AND METHOD OF USE THEREOF
PCT: Patent Cooperation Treaty
European Patent Office
16822043.2
3319510
7/8/2016
5/13/2020
7/8/2036
Granted
TISSUE ABLATION AND ASSESSMENT SYSTEM AND METHOD OF USE THEREOF
DIV: Divisional
European Patent Office
20173496.9
7/8/2016
Pending
TISSUE ABLATION AND ASSESSMENT SYSTEM AND METHOD OF USE THEREOF
PCT: Patent Cooperation Treaty
France
16822043.2
3319510
7/8/2016
5/13/2020
7/8/2036
Granted
TISSUE ABLATION AND ASSESSMENT SYSTEM AND METHOD OF USE THEREOF
PCT: Patent Cooperation Treaty
Germany
16822043.2
3319510
7/8/2016
5/13/2020
7/8/2036
Granted
TISSUE ABLATION AND ASSESSMENT SYSTEM AND METHOD OF USE THEREOF
PCT: Patent Cooperation Treaty
Italy
16822043.2
3319510
7/8/2016
5/13/2020
7/8/2036
Granted
TISSUE ABLATION AND ASSESSMENT SYSTEM AND METHOD OF USE THEREOF
PCT: Patent Cooperation Treaty
Netherlands
16822043.2
3319510
7/8/2016
5/13/2020
7/8/2036
Granted
TISSUE ABLATION AND ASSESSMENT SYSTEM AND METHOD OF USE THEREOF
PCT: Patent Cooperation Treaty
United Kingdom
16822043.2
3319510
7/8/2016
5/13/2020
7/8/2036
Granted
Tissue Ablation And Assessment System And Method Of Use Thereof
PCT: Patent Cooperation Treaty
United States
15/742,470
10,888,374
1/5/2018
1/12/2021
5/25/2037
Granted
TISSUE ABLATION AND ASSESSMENT SYSTEM AND METHOD OF USE THEREOF
CON: Continuation
United States
17/145,159
11,857,253
1/8/2021
1/2/2024
4/22/2037
Granted
TISSUE ABLATION AND ASSESSMENT SYSTEM AND METHOD OF USE THEREOF
CON: Continuation
United States
18/521,505
11/28/2023
Pending
Direct Link:
https://jhu.technologypublisher.com/technology/25112
Inventors:
Category(s):
Technology Classifications > Medical Devices, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Computers, Electronics & Software,
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For Information, Contact:
Louis Mari
lmari3@jhu.edu
410-614-0300
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