Harnessing Heterotopic Ossification with the Development of a Novel Bone Healing System Using Muscle Derived Cells (MDSCs), Bone Induction Agents, and Scaffolds

Case ID:
C13506
Disclosure Date:
3/31/2015
Description:
A bone healing, angiogenesis promoting and/or vasculogenesis performing system and methods of use thereof are provided, that employ a unique three-principled regenerative healing strategy of muscle-derived cells (e.g., fibroblast-depleted muscle derived stem cells (MDScs)), a bone induction agent (e.g., including ex vivo progenitor cell expansion with early osteo-induction), and a structurally robust scaffold (e.g., a collagen scaffold) support to achieve bone regeneration, angiogenesis promotion and/or vasculogenesis performance, thereby overcoming previous limitations in regenerative healing.
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For Information, Contact:
Vera Sampels
vsampel2@jhu.edu
410-614-0300
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