Wound Healing Compositions Comprising Biocompatible Cellulose Hydrogel Membranes and Methods of Use Thereof

Case ID:
C11070
Disclosure Date:
4/2/2010
Unmet Need
Corneal lacerations are a common type of eye injury. These can occur in varying degrees of severity, and in many cases the wound is non-self-sealing. This type of injury requires significant intervention including sutures and, in some cases, many layers of grafts. During the course of treatment patients are required to wear bandages that can obstruct vision and prevent an injured individual from completing essential tasks. Thus, there is a need for an ocular bandage with healing capabilities that is high in transparency and strength.
 
Technology Overview
Johns Hopkins University researchers have optimized the transparency, strength, and healing potential of a cellulose-based material for use in corneal wound healing. The material is cost-effective, promotes cell growth, and is biocompatible. Furthermore, the optical, biomechanical, and biological properties represent an improvement over current technologies and therefore the invention has great potential to be used as a therapeutic drug-releasing eye patch for corneal repair following injury/surgery.
 
Stage of Development
The technology has been prototyped and characterized in terms of optical transparency, heat flow, and biomechanical properties.
 
 
Patent Information:
Title App Type Country Serial No. Patent No. File Date Issued Date Expire Date Patent Status
Collagen Vitrigels with High Strength and Transparency for Ocular Reconstruction ORD: Ordinary Utility United States 13/295,515 9,211,256 11/14/2011 12/15/2015 11/14/2031 Granted
WOUND HEALING COMPOSITIONS COMPRISING BIOCOMPATIBLE CELLULOSE HYDROGEL MEMBRANES AND METHODS OF USE THEREOF DIV: Divisional United States 14/924,816 9,314,531 10/28/2015 4/19/2016 11/14/2031 Granted
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For Information, Contact:
Heather Curran
hpretty2@jhu.edu
410-614-0300
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