Artifact Control and Miniaturization of the Safe DC Stimulator for Neural Prostheses

Case ID:
C11822
Disclosure Date:
12/19/2011

Safe DC Stimulator for Neural Prostheses

JHU Ref #: [C11822]

 

Unmet Need

Currently, neural prostheses are limited because they excite neurons but cannot efficiently inhibit them. Direct current (DC) can excite, inhibit, or control extracellular potential of target neurons, but DC stimulation is biologically unsafe. The current solution is to direct DC stimulation into the target tissue by switching mechanical valves in phase with alternating current (AC) stimulations. This approach degrades the fidelity of the DC signal by periodic current flow. Therefore, there is a strong need for a system to remove interruptions in DC flow for optimal performance of neural prostheses.


Value Proposition

·        Provides precision and control of neural excitation and inhibition for use in neural prostheses.

·        Removes DC current flow from electrode-saline interface and streamlines DC ion flow into target tissue.

·        System of two safe DC stimulators working in tandem ensures fidelity of DC ion flow.

 

Technology Description

Researchers at Johns Hopkins have developed a neural prosthetic device for safer and more efficient treatment using DC stimulation by incorporating two safe DC stimulators in tandem. This DC stimulator system prevents DC ion flow at the interface, which is biologically harmful, while directing the current towards the target tissues simultaneously. This system of two DC stimulators working in tandem provides a safe and efficient method for neural prostheses.


Stage of Development

·        The researchers are in the prototype stage of development.

·        Looking for partners to develop & commercialize the technology as a neural prosthetic device for the development of cochlear implants and other devices such as retinal implants, transcranial stimulation electrical devices for functional MRI (fMRI), and anti-epileptic and anti-arrhythmic devices. 


Publication

N/A

Patent Information:
Title App Type Country Serial No. Patent No. File Date Issued Date Expire Date Patent Status
Artifact Control and Miniaturization of the Safe DC Stimulator for Neural Prostheses PCT: Patent Cooperation Treaty Australia 2012358886 2012358886 12/20/2012 2/1/2018   Granted
Artifact Control and Miniaturization of the Safe DC Stimulator for Neural Prostheses PCT: Patent Cooperation Treaty United States 14/366,870 9,572,979 6/19/2014 2/21/2017 8/14/2033 Granted
Artifact Control and Miniaturization of the Safe DC Stimulator for Neural Prostheses CON: Continuation United States 15/431,272 10,258,793 2/13/2017 4/16/2019 3/6/2033 Granted
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For Information, Contact:
Heather Curran
hpretty2@jhu.edu
410-614-0300
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