Unmet Need
Irritable Bowel Syndrome is a chronic and incurable gastrointestinal disorder that affects 3-20% of Americans depending on certain sociocultural and comorbid factors. A poorly understood condition, current treatments consist of antispasmodics, antidiarrheals, and dietary restrictions. Unable to alleviate all its symptoms, researchers are in continual search of new treatments for individuals suffering from IBS.
Technology Overview
Hopkins researchers have found a molecule, molybdate, that may reduce the hyperalgesia, or increased sensitization to pain, experienced in patients suffering from IBS. IBS-model mice that received molybdate treatment showed a significant reduction in their sensitivity to pain. These preliminary studies suggest that molybdate may become an effective treatment option for individuals with IBS.
Stage of Development
All studies have been performed in mouse models.
Publications
US Utility Application 2021/0308174
