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Dual-Target Vascular Endothelial Growth Factor (VEGF) Therapy for Treating Ocular Neovascularization
Value Proposition· Comprehensive Targeting: Engineered antagonist proteins combine elements of both VEGF receptor (VEGFR)-1 and VEGFR-2 to target all human VEGF ligands and sequester 2 ligand homodimers simultaneously.· Superior Inhibition: Comprehensive ligand blockade inhibits neovascularization more effectively than existing VEGF-A only...
Published: 4/24/2026
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Inventor(s):
Jamie Spangler
,
Raquel Formica
,
Peter Campochiaro
,
Paul Sargunas
Keywords(s):
Category(s):
Clinical and Disease Specializations > Ophthalmology
,
Clinical and Disease Specializations > Ophthalmology > Age-Related Macular Degeneration
,
Clinical and Disease Specializations > Ophthalmology > Choroidal Neovascularization
,
Clinical and Disease Specializations > Ophthalmology > Corneal Neovascularization
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Clinical and Disease Specializations > Ophthalmology > Diabetic Retinopathy
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Clinical and Disease Specializations > Ophthalmology > Dry Age-Related Macular Degeneration
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Clinical and Disease Specializations > Ophthalmology > Retinopathy
,
Clinical and Disease Specializations > Ophthalmology > Macular Degeneration
,
Clinical and Disease Specializations > Ophthalmology > Retinal Degeneration
,
Clinical and Disease Specializations > Ophthalmology > Retinal Vein Occlusion
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