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Epicopy, a Statistical Method to Identify Genomic Copy Number Variation (CNV) using High-density DNA Methylation Arrays

Genetic and epigenetic alterations have been implicated in carcinogenesis and integrated analyses of these have provided new insights into the mechanisms of cancer development. We developed Epicopy, a statistical method to identify copy number variation (CNV) using high-density Illumina 450K methylation arrays. Using Epicopy, we studied the instances...

Published: 10/4/2024 | Inventor(s): Christopher Umbricht, Leslie Cope, Soonweng Cho, Hyun-Seok Kim

Keywords(s): Cancers, Computer Systems Based on Biological Models, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Disease Indication, Physics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Computers, Electronics & Software