A Novel Method for Quantitatively Analyzing Multiple Genes for the Presence of Methylation in Biological Samples

Case ID:

C04348

Disclosure Date:

10/15/2003

C04348: Detection of Aberrantly Methylated Genes in Human Samples as Markers of Malignancy

Technical Details:
Inventors have identified novel genes that may be aberrantly methylated in cancer cells. A method for quantification and diagnosing such methylation has also been developed called quantitative multiplex-methylation specific PCR (QM-MSP).

Looking for Partners:
• This technology can be used to detect aberrant methylation in various body tissues including: blood, plasma, duct cells lymph, ductal lavage fluid, nipple aspiration fluid, breast tissue, lymph nodes, bone marrow, etc.
• Aberrent methylation can be detected in tissue containing as little as 50 – 1000 tumor cells resulting is a highly sensitive test.
• May allow for quick detection of cancer leading to rapid and aggressive cancer treatment which may increase chances of patient survival.
• This technology may also be used for disease staging and/or detecting therapy response.

Patent Information:

Title	App Type	Country	Serial No.	Patent No.	File Date	Issued Date	Expire Date	Patent Status
Quantitative Multiplex Methylation-Specific PCR	ORD: Ordinary Utility	United States	10/976,932	8,062,849	10/28/2004	11/22/2011	10/28/2024	Granted
Quantitative Multiplex Methylation-Specific PCR	CON: Continuation	United States	13/224,024	8,822,155	9/1/2011	9/2/2014	10/28/2024	Granted
Quantitative Multiplex Methylation-Specific PCR	DIV: Divisional	United States	14/469,009	9,416,404	8/26/2014	8/16/2016	10/28/2024	Granted

Direct Link:

https://jhu.technologypublisher.com/technology/16312

Inventors:

Category(s):

Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Research Tools > Assays, Technology Classifications > Diagnostics, Technology Classifications > Research Tools, Clinical and Disease Specializations > Oncology,

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For Information, Contact:

Nakisha Holder

nickki@jhu.edu

410-614-0300

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