🔍

N-Hydroxylsulfonamide Derivatives as New Physiologically Useful Nitroxyl Donors

Case ID:
C10220
Disclosure Date:
10/30/2007

Technology Overview


The invention relates to N-hydroxylsulfonamide derivatives that donate nitroxyl (HNO) under physiological conditions and are useful in treating and/or preventing the onset and/or development of diseases or conditions that are responsive to nitroxyl therapy, including heart failure and ischemia/reperfusion injury. Novel N-hydroxylsulfonamide derivatives release NHO at a controlled rate under physiological conditions, and the rate of HNO release is modulated by varying the nature and location of functional groups on the N-hydroxylsulfonamide derivatives.

Patent Information:
Title App Type Country Serial No. Patent No. File Date Issued Date Expire Date Patent Status
N-Hydroxylsulfonamide Derivatives as New Physiologically Useful Nitroxyl Donors PCT: Patent Cooperation Treaty Japan 2010-527222   9/26/2008   9/26/2028 Pending
N-Hydroxylsulfonamide Derivatives as New Physiologically Useful Nitroxyl Donors DIV: Divisional Japan 2014-025070 5878942 9/26/2008 2/5/2016 9/26/2028 Granted
N-Hydroxylsulfonamide Derivatives as New Physiologically Useful Nitroxyl Donors PCT: Patent Cooperation Treaty Mexico MX/a/2013/005760 334124 9/26/2008 10/15/2015 9/26/2028 Granted
N-Hydroxylsulfonamide Derivatives as New Physiologically Useful Nitroxyl Donors PCT: Patent Cooperation Treaty European Patent Office 08834117.7 2190814 9/26/2008 2/1/2017 9/26/2028 Granted
N-Hydroxylsulfonamide Derivatives as New Physiologically Useful Nitroxyl Donors ORD: Ordinary Utility United States 12/239,705 8,227,639 9/26/2008 7/24/2012 8/1/2030 Granted
N-Hydroxylsulfonamide Derivatives as New Physiologically Useful Nitroxyl Donors DIV: Divisional Korea (South) 10-2016-7010476 10-1813551 9/26/2008 12/22/2017 9/26/2028 Granted
N-Hydroxylsulfonamide Derivatives as New Physiologically Useful Nitroxyl Donors DIV: Divisional Korea (South) 10-2017-7036840 10-1905004 9/26/2008 9/28/2018 9/26/2028 Granted
N-Hydroxylsulfonamide Derivatives as New Physiologically Useful Nitroxyl Donors CON: Continuation United States 13/531,364 8,674,132 6/22/2012 3/18/2014 9/26/2028 Granted
N-Hydroxylsulfonamide Derivatives as New Physiologically Useful Nitroxyl Donors CON: Continuation United States 14/204,636 9,115,064 3/11/2014 8/25/2015 9/26/2028 Granted
N-Hydroxylsulfonamide Derivatives as New Physiologically Useful Nitroxyl Donors CON: Continuation United States 14/815,917 9,617,208 7/31/2015 4/11/2017 9/26/2028 Granted
Direct Link:
https://jhu.technologypublisher.com/technology/50277
Inventors:
Category(s):
Get custom alerts for techs in these categories/from these inventors:
For Information, Contact:
Mohit Ganguly
mgangul1@jh.edu
410-614-0300
Save This Technology:
Bookmark this page
JHTV Home | Search | Login/Subscribe
2017 - 2022 © Johns Hopkins Technology Ventures. All Rights Reserved. Powered by Inteum