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Aptamer Based Sickle Cell Anemia Therapeutic

INVENTION NOVELTY: This technology is a set of RNA aptamers capable of reducing sickle hemoglobin (HbS) polymerization, which has therapeutic potential in reducing vaso-occlusion and ischemia in sickle cell disease patients. VALUE PROPOSITION: Sickle cell anemia is a genetically inherited disease affecting 1 in 400 African American and up to 2% of the...

Published: 3/13/2025 | Inventor(s): James Casella, Shirley Purvis, Emily Barron-Casella, Yolanda Fortenberry, Jeffrey Keefer

Keywords(s): Biologics, Disease Indication, Genetic Disorders, Nucleic Acid, Sickle Cell Anemia, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Genetic Diseases > Sickle Cell Anemia, Clinical and Disease Specializations > Hematology, Clinical and Disease Specializations > Rare Diseases, Technology Classifications > Research Tools > Nucleic Acids, Technology Classifications > Therapeutic Modalities > Small Molecules, Clinical and Disease Specializations > Genetic Diseases, Technology Classifications > Research Tools, Technology Classifications > Therapeutic Modalities