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Gas6-functionalized extracellular vesicles for treatment of inflammatory conditions
Value Proposition· Superior Anti-Inflammatory Potency: This membrane-associated GAS6 demonstrates over 10-fold higher anti-inflammatory activity compared to equivalent amounts of soluble recombinant GAS6 proteins. · Dual Mechanism of Action: Inhibits pro-inflammatory cytokine production and concurrently stimulates anti-inflammatory responses,...
Published: 1/15/2026
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Inventor(s):
Kenneth Witwer
,
Matias Ostrowski
,
Martina Fabiano
,
Alan Adamczyk
Keywords(s):
Category(s):
Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms
,
Technology Classifications > Therapeutic Modalities > Targets
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Technology Classifications > Therapeutic Modalities > Biologics
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Clinical and Disease Specializations > Inflammation
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Clinical and Disease Specializations > Autoimmunity
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Clinical and Disease Specializations > Inflammation > Chronic Inflammatory Diseases
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Clinical and Disease Specializations > Inflammation > Arthritis
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Clinical and Disease Specializations > Inflammation > Tissue/Organ Transplant Rejection
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Clinical and Disease Specializations > Gastroenterology > Crohn's Disease
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Clinical and Disease Specializations > Gastroenterology > Ulcerative Colitis
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Clinical and Disease Specializations > Gastroenterology > Inflammatory Bowel Disease
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Clinical and Disease Specializations > Gastroenterology > Irritable Bowel Disease
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