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New Therapeutic Approach for the Treatment of Neuropathic Pain

Unmet NeedChronic pain affects around 50-million adults within the United States (see CDC). Currently the dominant treatment option for moderate to severe pain are opioids, which have a range of associated adverse effects as well as the potential for abuse. Despite the development of abuse-deterrent formulations, opioid dependence remains a major challenge....

Published: 3/13/2026 | Inventor(s): Takashi Tsukamoto, Barbara Slusher, Niyada Hin, Camilo Rojas, Xinzhong Dong, Yun Guan, Ilyas Berhane

Keywords(s): Agonists/Promoters, Chronic Pain, CNS and Neurological Disorders, Disease Indication, Small Molecules, Target, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations > Pain > Chronic Neuropathic Pain, Technology Classifications > Therapeutic Modalities > Targets, Technology Classifications > Therapeutic Modalities > Small Molecules

GsMtx-4 as a Treatment of Schwannomatosis Induced Pain

Value Proposition:· First Non-Surgical Therapy for Schwannomatosis Pain: Introduces the first targeted, injectable, mechanism-based treatment for schwannoma-associated pain, replacing the current reliance on tumor resection for pain control.· Mechanosensitive Ion Channel (MSC) Inhibition: GsMTx-4 uniquely blocks mechanosensitive ion channels...

Published: 3/13/2026 | Inventor(s): Kimberly Ostrow

Keywords(s):

Category(s): Clinical and Disease Specializations > Neurology > Neuropathy, Clinical and Disease Specializations > Genetic Diseases, Clinical and Disease Specializations > Neurology, Clinical and Disease Specializations > Pain > Chronic Neuropathic Pain, Clinical and Disease Specializations > Neurology > Hyperalgesia, Technology Classifications > Therapeutic Modalities > Peptides