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Method to Improve Brain Penetration of Nanoparticles
Unmet Need / Invention Novelty: Drug delivery to the brain is hindered by the brain’s wide perivascular space and protein-dense extracellular matrix, which limits diffusion of drugs from site of administration into the brain parenchyma. Methods are needed to improve the penetration of drugs into the brain parenchyma. Technical Details: Johns Hopkins...
Published: 9/26/2024   |   Inventor(s): Clark Zhang, Panagiotis Mastorakos, Jung Soo Suk, Justin Hanes
Keywords(s): Convection Enhanced Delivery (CED), Drug Delivery Mechanism, Drug Delivery Vehicle, Nanoparticles, Therapeutic Matter, Therapeutics
Category(s): Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Therapeutic Modalities
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