🔍
Search Results - clark+zhang
2
Results
Sort By:
Published Date
Updated Date
Title
ID
Descending
Ascending
Method to Improve Brain Penetration of Nanoparticles
Unmet Need / Invention Novelty: Drug delivery to the brain is hindered by the brain’s wide perivascular space and protein-dense extracellular matrix, which limits diffusion of drugs from site of administration into the brain parenchyma. Methods are needed to improve the penetration of drugs into the brain parenchyma. Technical Details: Johns Hopkins...
Published: 9/26/2024
|
Inventor(s):
Clark Zhang
,
Panagiotis Mastorakos
,
Jung Soo Suk
,
Justin Hanes
Keywords(s):
Convection Enhanced Delivery (CED)
,
Drug Delivery Mechanism
,
Drug Delivery Vehicle
,
Nanoparticles
,
Therapeutic Matter
,
Therapeutics
Category(s):
Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms
,
Technology Classifications > Therapeutic Modalities
Engineering Synthetic Brain Penetrating Gene Vectors
Unmet Need:Gene delivery to the central nervous system (CNS) has potential as a means for treating numerous debilitating neurological diseases. Viral gene delivery, though relatively efficient, has been limited by immunogenicity, low packaging capacity and difficulties in manufacture and scale-up. Non-viral gene vectors offer an attractive alternate...
Published: 9/26/2024
|
Inventor(s):
Graeme Woodworth
,
Clark Zhang
,
Panagiotis Mastorakos
,
Jung Soo Suk
,
Justin Hanes
Keywords(s):
Drug Delivery Vehicle Synthesis Method
,
Therapeutic Matter
,
Therapeutics
Category(s):
Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms
,
Technology Classifications > Therapeutic Modalities
JHTV Home
|
Search
|
Login/Subscribe
2017 - 2022 © Johns Hopkins Technology Ventures. All Rights Reserved. Powered by
Inteum