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Engineering Synthetic Brain Penetrating Gene Vectors

Unmet Need:Gene delivery to the central nervous system (CNS) has potential as a means for treating numerous debilitating neurological diseases. Viral gene delivery, though relatively efficient, has been limited by immunogenicity, low packaging capacity and difficulties in manufacture and scale-up. Non-viral gene vectors offer an attractive alternate...

Published: 3/13/2025 | Inventor(s): Graeme Woodworth, Clark Zhang, Panagiotis Mastorakos, Jung Soo Suk, Justin Hanes

Keywords(s): Drug Delivery Vehicle Synthesis Method, Therapeutic Matter, Therapeutics

Category(s): Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Therapeutic Modalities