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Identification of DNA Polymerase Theta Inactivation Mechanism

Unmet NeedLoss of DNA repair is an early and frequent event in the growth of tumors, occurring in 40 to 50% of breast, lung and ovarian cancer patients. The inability to repair damaged DNA provides a selective growth advantage to tumor cells as this results in genetic instability and enhanced mutation rates, which can drive tumor growth. These DNA...

Published: 9/26/2024 | Inventor(s): Marc Greenberg, Daniel Laverty

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Category(s): Technology Classifications > Therapeutic Modalities > Gene Therapies, Technology Classifications > Therapeutic Modalities > Cell Therapies