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Opioid Antagonists for Use in Patients Using Chimeric Antigen Receptor T and NK Cell Therapy

Unmet NeedCancer patients often experience extreme, chronic pain that is addressed through prescription opioids. These opioids can block receptors on NK and T cells, resulting in a reduced ability to initiate apoptosis and therefore a reduced immune response. This, combined with other factors including the cancer itself, chemotherapy and radiation treatments...

Published: 3/14/2025 | Inventor(s): Dermot Maher, Nicola Heller

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Pain, Clinical and Disease Specializations > Pain > Chronic Pain, Technology Classifications > Therapeutic Modalities > Gene Therapies