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Opioid Antagonists for Use in Patients Using Chimeric Antigen Receptor T and NK Cell Therapy
Unmet NeedCancer patients often experience extreme, chronic pain that is addressed through prescription opioids. These opioids can block receptors on NK and T cells, resulting in a reduced ability to initiate apoptosis and therefore a reduced immune response. This, combined with other factors including the cancer itself, chemotherapy and radiation treatments...
Published: 3/14/2025
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Inventor(s):
Dermot Maher
,
Nicola Heller
Keywords(s):
Category(s):
Clinical and Disease Specializations > Oncology
,
Clinical and Disease Specializations > Pain
,
Clinical and Disease Specializations > Pain > Chronic Pain
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Technology Classifications > Therapeutic Modalities > Gene Therapies
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