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Enhanced Fluorescence Signal through the Application of Aromatic Additives onto the Microscopy Sample for Standard Fluorescence, Fluorescence Microscopy, and Combined Fluorescence MALDI Microscopy/imaging

Value Proposition· Enhanced Fluorescence Intensity: Increases signal strength, enabling detection of molecules that are undetectable with traditional fluorescence microscopy and imaging techniques· Improved Efficiency: Requires less dye to achieve strong fluorescence signals and protects the sample from oxidative degradation, reducing reagent...

Published: 9/12/2025 | Inventor(s): Kristine Glunde, Ethan Yang, Caitlin Tressler, Scot Kuo, Hoku Kahele West-Foyle, Xinyi Shen

Keywords(s):

Category(s): Technology Classifications > Research Tools > Imaging, Technology Classifications > Research Tools > Assays, Technology Classifications > Research Tools > Buffers & Media Solutions, Technology Classifications > Research Tools > Proteins, Ligands & Receptors, Technology Classifications > Medical Devices > Imaging

Improved Raman Spectroscopy and Combined Raman-MALDI Imaging Workflow with the Addition of Aromatic Compounds

Unmet NeedRaman spectroscopy is a sensitive technique that provides the overall molecular vibrational signature of a sample. Its nondestructive nature has made it possible for in vivo imaging of cells and other small organisms. Furthermore, advances in this field have made high resolution mapping, known as Raman spectroscopy imaging (RSI), possible....

Published: 9/12/2025 | Inventor(s): Kristine Glunde, Ishan Barman, Ethan Yang, Jeong Hee Kim, Caitlin Tressler

Keywords(s):

Category(s): Technology Classifications > Medical Devices > Imaging