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Quantitative method to identify the source of hepatitis B surface antigen

Unmet Need / Invention Novelty: Loss of hepatitis B surface antigen (HBsAg) is defined as a functional cure for chronic hepatitis B virus infection, but it is clinically challenged by the derivation of HBsAg from two sources that must be uniquely targeted: covalently closed circular DNA (cccDNA) and integrated HBV DNA (iDNA). Currently, no rapid method...

Published: 3/14/2025 | Inventor(s): Ashwin Balagopal, Chloe Thio, Tanner Grudda, Hyon Hwang

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Category(s): Clinical and Disease Specializations > Infectious Diseases > Hepatitis B Virus, Technology Classifications > Diagnostics > Prognostic Biomarkers