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CRISPR/Cas9 and Tumor-Specific Guide RNAs as a Specific and Selective Cancer Cell Killing Biologic Platform
Value Proposition:Specific targeting of mutations can treat any cancer with the specified mutations.Selective cell killing spares healthy tissue while eliminating cancer cells. Pan-cancer efficacy as guide RNAs are developed to target a wide breadth of cancer-specific mutations.Lack of protospacer adjacent motif (PAM) sites in healthy host cells prevents...
Published: 3/14/2025
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Inventor(s):
James Eshleman
,
Selina Shiqing Teh
,
Kirsten Bowland
,
Nicholas Roberts
Keywords(s):
Category(s):
Clinical and Disease Specializations > Oncology
,
Clinical and Disease Specializations > Oncology > Pancreatic Ductal Adenocarcinoma
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Clinical and Disease Specializations > Oncology > Pancreatic Cancer
,
Technology Classifications > Therapeutic Modalities > Biologics
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Technology Classifications > Research Tools > Nucleic Acids
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