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Repurposing Thiazolidinedione for the Treatment of Muscular Dystrophies
JHU Ref #: C17163Value Proposition· Improves specific isometric force and muscle-fiber cross-sectional area.· Reduces necrosis and inflammation in early disease, as well as diaphragm fibrosis in advanced disease. · Doubles the proportion of dystrophin-positive fibers and nearly doubles functional endurance when combined with AAV...
Published: 6/27/2025
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Inventor(s):
Laszlo Nagy
,
Lee Sweeney
,
David Hammers
,
Andreas Patsalos
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