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Repurposing Thiazolidinedione for the Treatment of Muscular Dystrophies

JHU Ref #: C17163Value Proposition· Improves specific isometric force and muscle-fiber cross-sectional area.· Reduces necrosis and inflammation in early disease, as well as diaphragm fibrosis in advanced disease. · Doubles the proportion of dystrophin-positive fibers and nearly doubles functional endurance when combined with AAV...

Published: 9/12/2025 | Inventor(s): Laszlo Nagy, Lee Sweeney, David Hammers, Andreas Patsalos

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Category(s): Clinical and Disease Specializations > Genetic Diseases > Duchenne Muscular Dystrophy