Search Results - mark+markowski

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Intranasal Delivery of Testosterone Prodrugs to the CNS

Unmet NeedProstate cancer (PC) is the most common non-cutaneous malignancy in men with over 1.4 million new cases diagnosed globally in 2020 (see Wang 2022). Although disease confined to the prostate is highly curable, many men will be diagnosed with metastatic prostate cancer which is not curable but is treatable. The gold standard of care is androgen...

Published: 3/14/2025 | Inventor(s): Rana Rais, Barbara Slusher, Mark Markowski, Arindom Pal

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology > Prostate Cancer, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Therapeutic Modalities > Small Molecules

Sequential Hormone Therapy to Improve Survival and Enhance Response to Immune Therapy in Men with Prostate Cancer

Unmet Need / Invention Novelty: Men with prostate cancer develop resistance to androgen deprivation therapy (castration resistant prostate cancer) and must rely on less defined subsequent lines of therapy. Increasing resistance develops with each subsequent line of hormonal therapy. There exists an unmet clinical need to overcome resistance to hormone...

Published: 3/14/2025 | Inventor(s): Samuel Denmeade, John Isaacs, Emmanuel Antonarakis, Sushant Kachhap, Mark Markowski

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Oncology > Prostate Cancer, Technology Classifications > Therapeutic Modalities