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Search Results - sarah+neshat
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Polymers and Nanoparticles for Intramuscular Nucleic Acid Delivery
Value Proposition:· Platform technology for prophylactic and therapeutic vaccination with large RNA payloads.· Can deliver several types of nucleic acid payloads including self-amplifying mRNA, plasmid, linear DNA, siRNA, miRNA, mRNA.· Adaptable as a therapeutic delivery strategy for genetic, musculoskeletal, and neurological disorders.Unmet Need:Vaccinology...
Published: 3/14/2025
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Inventor(s):
Jordan Green
,
David Wilson
,
Stephany Tzeng
,
Yuan Rui
,
Sarah Neshat
,
Kathryn Luly
Keywords(s):
Category(s):
Clinical and Disease Specializations > Immunology
,
Clinical and Disease Specializations > Infectious Diseases
Polymeric Nanoparticle Genetic Vaccines
Value PropositionVersatile immunotherapy platform with the ability to specifically target antigen presenting cells (APCs) ) following systemic delivery and without requiring targeting ligands to improve treatment efficacy. Flexibility to modulate the immune system through activation or inducing tolerance.Useful as a preventative strategy or therapeutic...
Published: 3/14/2025
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Inventor(s):
Jordan Green
,
Elana Ben-Akiva
,
Johan Karlsson
,
Stephany Tzeng
,
Kelly Rhodes
,
Sarah Neshat
Keywords(s):
Category(s):
Clinical and Disease Specializations > Autoimmunity
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Clinical and Disease Specializations > Immunology
,
Technology Classifications > Medical Devices > Therapeutic Devices
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Technology Classifications > Therapeutic Modalities > Dendrimers & Polymers
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Technology Classifications > Therapeutic Modalities > Immunotherapies
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Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms
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Technology Classifications > Therapeutic Modalities > Vaccines
Crystallization of the Multi-receptor Tyrosine Kinase Inhibitor Sorafenib for Controlled Long-term Drug Delivery following a Single Injection
#C16812Inventor(s): Victoria Lai,
Sarah Neshat
, and Joshua C. DoloffUnmet NeedCancer is the second worldwide cause of death, exceeded only by cardiovascular diseases. Despite technological advancements, the challenge remains to create anti-cancer drugs, or antineoplastics, that are safe, effective, and deliverable to the correct tissue at the right...
Published: 3/14/2025
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Inventor(s):
Joshua Doloff
,
Victoria Lai
,
Sarah Neshat
,
Elia Duh
,
Amanda Rakoski
,
James Pitingolo
,
Lingli Zhou
,
Haining Lu
Keywords(s):
Category(s):
Clinical and Disease Specializations > Oncology
,
Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms
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