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Stimulation of Dendrite Growth and Spine Formation by Norrin and LGR6: A Target for Therapy in CNS Injury and Degeneration
Unmet NeedAstroglial dysfunction is associated with the development of numerous central nervous system (CNS) diseases, including amyotrophic lateral sclerosis (ALS), Parkinson’s disease (PD), and Huntington’s disease (HD). Astroglia are the homeostatic cells of the central nervous system and play key roles in the development and support of neuronal...
Published: 3/14/2025
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Inventor(s):
Sean Miller
,
Jeffrey Rothstein
Keywords(s):
Alzheimer's Disease
,
Amyotrophic Lateral Sclerosis
,
Biologics
,
CNS and Neurological Disorders
,
Dementia
,
Disease Indication
,
Huntington's Disease
,
Parkinson's Disease
,
Protein
,
Target
,
Therapeutic Matter
,
Therapeutic Substance
,
Therapeutics
Category(s):
Clinical and Disease Specializations > Neurology > Neurodegeneration
,
Clinical and Disease Specializations > Neurology > Amyotrophic Lateral Sclerosis
,
Clinical and Disease Specializations > Neurology > Dementia
,
Technology Classifications > Therapeutic Modalities > Proteins
,
Clinical and Disease Specializations > Neurology > Alzheimer's Disease
,
Technology Classifications > Therapeutic Modalities > Targets
,
Clinical and Disease Specializations > Neurology > Huntington's Disease
,
Clinical and Disease Specializations > Neurology > Parkinson’s Disease
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