Search Results - sridevi+sarma

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Source-sink Analysis for Localization of the Epileptogenic Zone on Interictal Data

Unmet NeedEpilepsy is a devastating disease that affects over 50 million people globally. 70% of patients diagnosed with epilepsy can treat their symptoms with medication, but around 30% of patients have symptoms that do not respond to drugs. Recent studies have found that the most effective treatments for drug resistant epilepsy are interventions that...

Published: 3/14/2025 | Inventor(s): Sridevi Sarma, Kristin Gunnarsdottir, Jorge Gonzalez-Martinez

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Category(s): Technology Classifications > Computers, Electronics & Software

Dynamical Systems Modeling of the Epileptic Brain for Seizure Onset Localization

Unmet NeedEvery year, around 5 million people are diagnosed with epilepsy globally. About 30% of the global epileptic population have medically refractory epilepsy (MRE) with seizures that cannot be controlled with medication. MRE patients have two treatment options: surgical resection of or electrical stimulation of the seizure onset zone (SOZ). Both...

Published: 3/14/2025 | Inventor(s): Sridevi Sarma, Golnoosh Kamali, Rachel Smith, Joon Kang

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Category(s): Technology Classifications > Computers, Electronics & Software, Technology Classifications > Diagnostics

Closed-loop Peripheral Nerve Stimulation for Restoration in Chronic Pain

Unmet NeedChronic pain affects about 100-million adults in the United States and is primarily treated with drugs, which can have significant negative side effects (NIH-Institute of Medicine). A promising alternative therapy is electrical peripheral nerve stimulation (PNS) therapy. However, PNS therapy has been associated with suboptimal efficacy because...

Published: 3/14/2025 | Inventor(s): Sridevi Sarma, Christine Beauchene, Yun Guan, Claire Zurn

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Category(s): Clinical and Disease Specializations > Pain > Chronic Pain, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Medical Devices > Neurostimulation, Technology Classifications > Medical Devices > Therapeutic Devices

Virtual Cortical Stimulation Mapping for Epileptogenic Zone Localization

Unmet NeedCortical stimulation mapping is an electrocorticography monitoring that involves a surgically invasive clinical procedure. Its purpose serves to localize functions of specific cerebral regions of the brain through electrical stimulation of a cerebral cortex. During cortical stimulation mapping, electrodes are placed directly on to the cerebral...

Published: 3/14/2025 | Inventor(s): Sridevi Sarma, Adam Li

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Category(s): Technology Classifications > Computers, Electronics & Software > Algorithms, Clinical and Disease Specializations > Neurology > Epilepsy