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Long Term Storage and Improved Mechanical Properties of Implantable Vascular Grafts

Technical Problem Current synthetic small-diameter tissue engineered vascular grafts face challenges such as thrombogenicity, decreased elasticity, aneurysmal failure, calcification, and intimal hyperplasia, limiting their clinical effectiveness for pediatric congenital cardiovascular defects, coronary artery disease, and peripheral artery disease,...

Published: 1/27/2026 | Inventor(s): Sharon Gerecht, Morgan Elliott, Hai-Quan Mao, Jessica Shen

Keywords(s):

Category(s): Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Therapeutic Modalities > Tissue Substrates, Technology Classifications > Medical Devices > Cardiology

Liquid-infused Porous Piezoelectric Scaffolds with their Applications

Value Proposition· This technology demonstrates superior mechanical properties and has a simpler manufacturing process as compared to other mechanically adaptive materials.· Unlike other existing materials, this technology enhances its own mechanical properties with cyclic loading, thus reducing the costs associated with failure and repeated...

Published: 1/22/2026 | Inventor(s): Sung Hoon Kang, Bohan Sun

Keywords(s):

Category(s): Technology Classifications > Medical Devices > Orthopedic Devices, Technology Classifications > Therapeutic Modalities > Tissue Substrates, Technology Classifications > Engineering Tech > Materials

Dynamic Hydrogels

Unmet NeedOrgan/tissue regeneration remains a major area of research with few viable clinical products. A major barrier is the development of biologically accurate tissue constructs, with vascularization being a primary component. Classic static hydrogels have non-reversible crosslinks such that network is elastic at the macro-scale but limited in response...

Published: 1/22/2026 | Inventor(s): Sharon Gerecht, Rahel Schnellmann, Zhao Wei, Eugenia Volkova

Keywords(s):

Category(s): Technology Classifications > Medical Devices > Regenerative Medicine, Technology Classifications > Therapeutic Modalities > Tissue Substrates, Clinical and Disease Specializations > Wound Healing, Clinical and Disease Specializations > Cardiovascular > Vascular Diseases

Biomimetic, Mussel-inspired, Bioactive Bone Graft Substitute Materials for Bony Fusion

Unmet NeedSpinal fusion is the welding together of adjacent vertebrae. Each year, more than 400,000 Americans undergo spinal fusion to treat conditions like neck and back pain, spinal instability, radiculopathy, and myelopathy. These surgeries require many items, such as spinal rods, screws, and cages. In addition, they require a bone graft to fill...

Published: 1/22/2026 | Inventor(s): Timothy Witham, Ethan Cottrill

Keywords(s):

Category(s): Technology Classifications > Therapeutic Modalities > Tissue Substrates, Clinical and Disease Specializations > Musculoskeletal