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An ECL-based Autoantibody Assay for Early Diagnosis of T1D Using a Membrane-spanning ZnT8 Antigenic Domain
Unmet NeedApproximately 1.25 million people in the US have type 1 diabetes (T1D) and the rates of newly diagnosed cases in children are on the rise each year. T1D is caused by the development of an autoimmune reaction to pancreatic β cells. The first detectable sign of β cell autoimmunity is the appearance of diabetes-associated autoantibodies, which...
Published: 9/27/2024
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Inventor(s):
Dax Fu
,
Chengfeng Merriman
,
Liping Yu
,
Yong Gu
Keywords(s):
Assay
,
Biomarker
,
Clinical Diagnostics
,
Diabetes
,
Diagnostic Biomarker
,
Diagnostic Tool
,
Disease Indication
,
In Vitro Diagnostics (Old)
,
Measurement Tool
,
Metabolic Disorders
,
Type II Diabetes
Category(s):
Clinical and Disease Specializations > Diabetes > Type 1 Diabetes
,
Technology Classifications > Diagnostics > In Vitro Diagnostics
,
Technology Classifications > Diagnostics > In Vivo Diagnostics
,
Clinical and Disease Specializations > Diabetes > Type 2 Diabetes
,
Technology Classifications > Diagnostics > Diagnostic Biomarkers
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