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Dendrimer-conjugated GCPII Inhibitors to Delay Loss of Muscle Mass and Strength

Value Proposition· GCPII inhibitor has a low IC50 (<5 nM), suggesting greater potency and less systemic toxicity.· Functional improvements after treatment include 95% preservation of muscle mass, 96% preservation of grip strength, 25% greater isometric force.· Decreased decline in neuromuscular transmission compared to control. Technology...

Published: 3/13/2026 | Inventor(s): Barbara Slusher, Yu Su, Kannan Rangaramanujam

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Category(s): Clinical and Disease Specializations > Musculoskeletal > Muscle Atrophy, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms