Search Results - zachary+schneiderman

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ssDNA Nanotubes Targeting Brain Tumors and Other Cancers Selectively
Unmet NeedA large number of cancers, including glioblastoma (GBM), lack effective treatment due to inaccessibility of the primary tumor to pharmaceutical interventions. GBM is highly malignant, leading to 5-year survival rates below 10%. The inability to treat GBM tumors effectively is largely due to the blood brain barrier (BBB). Common approaches...
Published: 9/27/2024   |   Inventor(s): Efrosini Kokkoli, Zachary Schneiderman
Keywords(s):  
Category(s): Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Oncology > Brain Cancer, Technology Classifications > Therapeutic Modalities
Targeted Liposomes Encapsulating miR-603 Complexes
Unmet Need: Glioblastoma (GBM) is the most common malignant brain tumor in adults, affecting 17K patients in the US annually. GBM stem cells underlie GBM recurrence, leading to treatment resistance and poor patient outcomes. Standard treatments remove the primary tumor cells but leave space for GBM stem cells to cause tumorigenesis. There is a need...
Published: 9/27/2024   |   Inventor(s): Efrosini Kokkoli, Clark Chen, Zachary Schneiderman
Keywords(s):  
Category(s): Clinical and Disease Specializations > Neurology, Clinical and Disease Specializations > Oncology > Glioblastoma, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities
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