Technical Details:
Surprisingly, it has been found that the Barx2 gene is mutated in ovarian cancer. The invention provides methods of diagnosis, prognosis and treatment of cancer related to the Barx2 gene.
Looking for Partners:
This technology could be commercialized as diagnostic and prognostic kits and therapeutics for cancer related to the Barx2 gene.
Publications/Associated Cases:
Krasner A, Wallace L, Thiagalingam A, Jones C, Lengauer C, Minahan L, Ma Y, Kalikin L, Feinberg AP, Jabs EW, Tunnacliffe A, Baylin SB, Ball DW, Nelkin BD. Cloning and chromosomal localization of the human BARX2 homeobox protein gene. Gene. 2000 May 30;250(1-2):171-80.