Mass-Correlated Pulsed Extraction for a Time-of-Flight Mass Spectrometer

Case ID:
C03548

C03548: Mass-Correlated Pulsed Extraction for a Time-of-Flight Mass Spectrometer

Value Proposition:

ADVANTAGES
• Innovative spectrometer technology addresses recognized problem of inequity of multiple ion distribution parameters that reduces resolution of mass spectra data by optimizing the ion velocity distribution and improving velocity focusing along the entire ion mass range of interest for better resolution and more accurate data.
• Technology employs a two-source extraction scheme with a dynamic second electric field to compensate for the mass dependency of pulsed extraction methods making the instrument better suited for identification and quantification of complex mixtures which are often recorded over a broad mass range.
• Patented invention is part of a portfolio of Dr. Robert Cotter’s mass spectrometry technologies

Technical Details:

This method and apparatus provides improved focusing and mass resolution over a broad mass range for a time-of-flight mass spectrometer. This is accomplished in a two-source extraction scheme in which the second field is dynamic and compensates for the mass dependency of pulsed extraction methods. The technique is particularly helpful when instruments are utilized for complex mixtures, tryptic digests and oligonucleotide sequencing ladders that are recorded over a broad mass range.

Looking for Partners:

This patented instrument and method can be used for a wide range of research and analytical tasks, especially for identification and quantification of complex protein mixtures.



Patent Information:
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For Information, Contact:
Louis Mari
lmari3@jhu.edu
410-614-0300
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