Technical Details:
Recombinant E. phagocytophilia MSP is a major immunodominant protein antigen derived from the human E. phagocytophilia (HE agent) strain BDS. The clone was initially selected based upon reactivity with monoclonal antibody to E. phagocytophilia group antigens and the gene sequenced and subcloned into the pMAL vector (New England Bio) and expressed in E. coli.
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The recombinant protein is a fusion with maltose binding protein and may be used for serologic studies to confirm the diagnosis of human granulocytic ehrlichiosis
