Identification of DNA Sequences Differentially Methylated in Pancreatic Cancer

Case ID:

C03825

C03825: Identification of DNA Sequences Differentially Methylated in Pancreatic Cancer
Technical Details:
Researchers at Johns Hopkins University have used the techniques of methylated CpG island amplification (MCA) coupled with representational difference analysis (RDA) to isolate 42 clones, which were shown to be differentially methylated in a panel of 8 pancreatic cancer cell lines compared to normal pancreas. Ninety-five percent of the clones were CpG islands and among these clones were CpG islands of several known genes. The genes identified may represent novel targets for pancreatic cancer treatment or serve as diagnostics for the detection of early stage pancreatic cancer.

Patent Information:

Title	App Type	Country	Serial No.	Patent No.	File Date	Issued Date	Expire Date	Patent Status
Differentially Methylated Sequences in Pancreatic Cancer	ORD: Ordinary Utility	United States	10/084,555	7,153,653	2/25/2002	12/26/2006	2/23/2022	Granted

Direct Link:

https://jhu.technologypublisher.com/technology/16201

Inventors:

Category(s):

Clinical and Disease Specializations, Clinical and Disease Specializations > Gastroenterology, Clinical and Disease Specializations > Oncology > Pancreatic Cancer, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Therapeutic Modalities > Targets, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities,

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For Information, Contact:

Michael Woods

mwoods19@jh.edu

410-614-0300

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