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R-3327-MAT-Lu
Case ID:
C03852
Report of Invention:
3/8/2001
Web Published:
10/7/2014
C03852: R-3327-MAT-Lu
Technical Details:
This cell line was derived from the "H" subline and upon passage to the AT-1 subline (JHU-29) of the parental R3327 tumor. The "H" subline is a heterogeneous cell line as it is comprised of androgen-dependent and androgen-independent tumor cells. Passing this AT-1 sublinein intactmale rats allowed for the cloning of androgen-independent cell lines which gave rise to a fast-growing metastatic, anaplastic tumor (MAT) cell line which was further characterized to be highly metastatic to the lung (MAT-Lu). This cell line is a valuable model for the studying prostate malignancies both in vitro, and in vivo.DM 3852
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Direct Link:
https://jhu.technologypublisher.com/technology/16207
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Category(s):
Clinical and Disease Specializations, Clinical and Disease Specializations > Men's Health, Clinical and Disease Specializations > Oncology > Prostate Cancer, Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Cell Lines, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools,
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For Information, Contact:
Christine Joseph
cjoseph6@jhmi.edu
410-614-0300
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