R-3327-MAT-Lu

Case ID:

C03852

Disclosure Date:

3/8/2001

C03852: R-3327-MAT-Lu
Technical Details:
This cell line was derived from the "H" subline and upon passage to the AT-1 subline (JHU-29) of the parental R3327 tumor. The "H" subline is a heterogeneous cell line as it is comprised of androgen-dependent and androgen-independent tumor cells. Passing this AT-1 sublinein intactmale rats allowed for the cloning of androgen-independent cell lines which gave rise to a fast-growing metastatic, anaplastic tumor (MAT) cell line which was further characterized to be highly metastatic to the lung (MAT-Lu). This cell line is a valuable model for the studying prostate malignancies both in vitro, and in vivo.DM 3852

Direct Link:

https://jhu.technologypublisher.com/technology/16207

Inventors:

Category(s):

Clinical and Disease Specializations, Clinical and Disease Specializations > Men's Health, Clinical and Disease Specializations > Oncology > Prostate Cancer, Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Cell Lines, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools,

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For Information, Contact:

Christine Joseph

cjoseph6@jhmi.edu

410-614-0300

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