C04219: Pathological Heart Condition Diagnostic DeviceNovelty:
This technology is a device that uses a portable electrocardiogram, heart sound measurement unit, and a time frequency based algorithm to detect, evaluate, and diagnose the heart for pathological conditions.
Value Proposition:
Studies show that primary care physicians frequently refer patients to cardiac specialists on the basis of suspicious heart sounds detected by traditional stethoscope auscultation. There is a need to automate auscultation in order to improve care, reduce costs, and prevent delays in diagnosis; however, no device to automate auscultation is currently available. This current technology, developed at JHU, is a portable device that can perform automatic screening of pathological heart conditions using heart sound data. The advantages of this device include:
• Reduce cost, and time for patients and physicians
• Readily implementable by those of ordinary skill
• Simplicity and automation allow diagnosis when a trained professional is not available
• Portability allows access to remote and underserved areas
• As patient database grows, device provides greater reliability and accuracy
• Easy integration with other telemedicine regimes
• Easy integration of information and communication technology
Technical Details:
Johns Hopkins researchers have developed a device in which a time series of heart sounds and ECG peaks are filtered and parsed into a sequence of individual heart cycles. These systolic heart cycles are then digitally filtered and optimized and ultimately fed through multiple processes and input into a Neyman-Pearson constant false alarm rate detector. Eventually a click score is determined and if this click score falls less than a given threshold, a no-click indicator is displayed. If the click score is above a given threshold, then a click present indicator is displayed. An indication of click present would allow users of the device to refer the patient to a cardiac specialist for further investigation.
Looking for Partners:
To develop and commercialize the technology as a novel, portable diagnostic device for determining pathological cardiac disease.
Stage of Development:
Pre-Clinical
Data Availability:
Under CDA/NDA
Publications/Associated Cases:
Biomed Instrum Technol. 2003 Jul-Aug;37(4):263-70
