Probe for measuring Bioimpedance of the Human Uterine Cervix

Case ID:
C04241
Disclosure Date:
5/1/2003
C04241: Probe for measuring Bioimpedance of the Human Uterine Cervix
Technical Details:
There are various clinical conditions, both normal and abnormal, where significant remodeling of the proteins in the human uterine cervix occurs. For example, with increased secretion of decorin in late pregnancy and labor, collagen (the main component of the extracellular matrix of cervical tissue) is hydrolyzed and replaced by hyaluronic acid, which has a high attraction for water molecules. The resultant increase in water content of cervical tissue improves its ability to conduct electrical current. A bioimpedance probe has been designed to detect subtle changes in tissue composition, and thereby detect the onset of cervical remodeling in a non-invasive manner and much earlier than existing clinical methods.
Looking for Partners:
Monitoring pre-term labor and Detection of cervical cancer
Patent Information:
Title App Type Country Serial No. Patent No. File Date Issued Date Expire Date Patent Status
Devices, systems and methods for bioimpedance measurement of cervical tissue and methods for diagnosis and treatment of human cervix PCT: Patent Cooperation Treaty United States 10/555,503 8,060,195 11/26/2008 11/15/2011 2/14/2027 Granted
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For Information, Contact:
Louis Mari
lmari3@jhu.edu
410-614-0300
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