Hypermethylation of GATA-4 Transcription Factor Gene in Cancer

Case ID:

C04309

Disclosure Date:

8/12/2003

Methods are provided for identifying the presence of cancer cells in a sample by detecting hypermethylation of the promoter region of a GATA-4 transcription factor gene, a GATA-5 transcription factor gene, or both. Methods for ameliorating a cancer by effecting expression of a hypermethylation silenced GATA-4 and/or GATA-5 transcription also are provided.

Patent Information:

Title	App Type	Country	Serial No.	Patent No.	File Date	Issued Date	Expire Date	Patent Status
Hypermethylation of GATA-4 and GATA-5 Transcription Factor Genes in Cancer	ORD: Ordinary Utility	United States	10/972,066	7,371,527	10/21/2004	5/13/2008	4/9/2025	Granted
Hypermethylation of GATA-4 and GATA-5 Transcription Factor Genes in Cancer	DIV: Divisional	United States	12/119,366	8,071,290	5/12/2008	12/6/2011	8/24/2025	Granted

Direct Link:

https://jhu.technologypublisher.com/technology/16302

Inventors:

Category(s):

Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics,

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For Information, Contact:

Nakisha Holder

nickki@jhu.edu

410-614-0300

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