293 EcR Shh

Case ID:

C04408

C04408: 293 EcR Shh
Technical Details:
Cell line for ecdysone-inducible expression of Shh.
Looking for Partners:
This cell line can be used to discover compounds that block activation of the Hh response pathway and abnormal cell growth associated with both types of oncogenic mutation.
Publications/Associated Cases:
Taipale et al. 2000 “Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine.” Nature. 2000 Aug 31;406(6799):1005-9

Direct Link:

https://jhu.technologypublisher.com/technology/16327

Inventors:

Category(s):

Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Human Cell Lines, Technology Classifications > Research Tools,

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For Information, Contact:

Nakisha Holder

nickki@jhu.edu

410-614-0300

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