Mutational analysis of the tyrosine phosphatome in colorectal cancers

Case ID:

C04435

Technical Details:
JHU researchers have performed a comprehensive mutational analysis of the protein tyrosine phosphatases super gene family in colorectal tumors and other cancers. It was discovered that the mutated tyrosine phosphatases are tumor suppressor genes, regulating pathways that may be amendable to therapeutic intervention

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Provides the basis for new therapeutic and diagnostic approaches for colorectal cancer.

Publications:
Science. 2004 May 21;304(5674):1164-6

Patent Information:

Title	App Type	Country	Serial No.	Patent No.	File Date	Issued Date	Expire Date	Patent Status
Protein Tyrosine Phosphatase Mutations in Cancers	PCT: Patent Cooperation Treaty	United States	11/596,349	8,039,210	11/14/2006	10/18/2011	5/16/2025	Granted
Protein Tyrosine Phosphatase Mutations in Cancers	CON: Continuation	United States	13/275,958	9,012,145	10/18/2011	4/21/2015	5/16/2025	Granted

Direct Link:

https://jhu.technologypublisher.com/technology/16337

Inventors:

Category(s):

Clinical and Disease Specializations, Clinical and Disease Specializations > Gastroenterology, Clinical and Disease Specializations > Oncology > Colorectal Cancer, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Research Tools > Nucleic Acids, Technology Classifications > Therapeutic Modalities > Proteins, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools, Technology Classifications > Therapeutic Modalities,

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For Information, Contact:

Jeanine Pennington

jpennin5@jhmi.edu

410-614-0300

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