BACE2 Knockout Mice

Case ID:

C04556

C04556: BACE2 Knockout Mice
Technical Details:
Two beta-secretases termed BACE1 and BACE2 have been shown to generate the Alzheimer's disease Abeta peptides. To examine the physiological roles of BACE2 and to determine whether BACE2 is the major beta-secretase in neurons, Johns Hopkins University researchers have created mice with targeted inactivation of both BACE2 alleles
Looking for Partners:
These knock out mice may be used for the assessment of potential mechanism based toxcicity associated with anti-BACE1 therapy in Alzheimer's Disease.

Direct Link:

https://jhu.technologypublisher.com/technology/16357

Inventors:

Category(s):

Clinical and Disease Specializations, Clinical and Disease Specializations > Geriatrics, Clinical and Disease Specializations > Neurology > Alzheimer's Disease, Clinical and Disease Specializations > Neurology > Neurodegeneration, Clinical and Disease Specializations > Rare Diseases, Technology Classifications > Research Tools > Animal Models, Clinical and Disease Specializations > Neurology, Technology Classifications > Research Tools,

Get custom alerts for techs in these categories/from these inventors:

Subscribe for JHTV Updates

For Information, Contact:

Michael Woods

mwoods19@jh.edu

410-614-0300

Save This Technology:

Bookmark this page

Download as PDF