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Unexpected Cross-neutralization of Cutaneous & Mucosal Papillomavirus Types with Anti-Sera to a Novel L2 Epitopes
Case ID:
C04603
Report of Invention:
12/21/2004
Web Published:
10/7/2014
C04603: Unexpected Cross-neutralization of Cutaneous & Mucosal Papillomavirus Types with Anti-Sera to a Novel Epitopes
Technical Details:
High risk Human Papillomavirus (HPV) infection is a common cause of cervical cancer. Researchers at JHU have found that vaccination with the N terminus of HPV16 and bovine papillomavirus 1 can induce cross neutralizing antibodies that inhibit in vitro generated pseudovirus infection of both cutaneous and genital types that infect both humans and animals.
Looking for Partners:
The invention could be developed into a simple protein-based vaccine to broadly prevent genital and cutaneous papillomavirus infections. The fact that the vaccination appears to have such a wide spectrum of activity against animal papillomavirus suggests that it could be developed for veterinarian use as well.
Patent Information:
Title
App Type
Country
Serial No.
Patent No.
File Date
Issued Date
Expire Date
Patent Status
Papillomavirus L2 N-Terminal Peptides for the Induction of Broadly Cross-Neutralizing Antibodies
PCT: Patent Cooperation Treaty
Australia
2006210792
2006210792
2/1/2006
11/8/2012
2/1/2026
Granted
Papillomavirus L2 N-Terminal Peptides for the Induction of Broadly Cross-Neutralizing Antibodies
PCT: Patent Cooperation Treaty
European Patent Office
06734177.6
1853307
2/1/2006
12/14/2016
2/1/2026
Granted
Papillomavirus L2 N-Terminal Peptides for the Induction of Broadly Cross-Neutralizing Antibodies
PCT: Patent Cooperation Treaty
China
200680011079.1
ZL 200680011079.1
2/1/2006
3/27/2013
2/1/2026
Granted
Papillomavirus L2 N-Terminal Peptides for the Induction of Broadly Cross-Neutralizing Antibodies
PCT: Patent Cooperation Treaty
Canada
2,596,698
2,596,698
2/1/2006
5/16/2017
2/1/2026
Granted
Papillomavirus L2 N-Terminal Peptides for the Induction of Broadly Cross-Neutralizing Antibodies
PCT: Patent Cooperation Treaty
Japan
2007-554194
5224821
2/1/2006
3/22/2013
2/1/2026
Granted
Papillomavirus L2 N-Terminal Peptides for the Induction of Broadly Cross-Neutralizing Antibodies
PCT: Patent Cooperation Treaty
Brazil
PI0607097-3
PI 0607097-3
2/1/2006
9/24/2020
2/1/2026
Granted
Papillomavirus L2 N-Terminal Peptides for the Induction of Broadly Cross-Neutralizing Antibodies
PCT: Patent Cooperation Treaty
India
6219/DELNP/2007
263255
2/1/2006
10/16/2014
2/1/2026
Granted
Papillomavirus L2 N-Terminal Peptides for the Induction of Broadly Cross-Neutralizing Antibodies
PCT: Patent Cooperation Treaty
France
06734177.6
1853307
2/1/2006
12/14/2016
2/1/2026
Granted
Papillomavirus L2 N-Terminal Peptides for the Induction of Broadly Cross-Neutralizing Antibodies
PCT: Patent Cooperation Treaty
United Kingdom
06734177.6
1853307
2/1/2006
12/14/2016
2/1/2026
Granted
Papillomavirus L2 N-Terminal Peptides for the Induction of Broadly Cross-Neutralizing Antibodies
PCT: Patent Cooperation Treaty
Germany
06734177.6
1853307
2/1/2006
12/14/2016
2/1/2026
Granted
Papillomavirus L2 N-Terminal Peptides for the Induction of Broadly Cross-Neutralizing Antibodies
PCT: Patent Cooperation Treaty
United States
11/883,495
8,404,244
5/13/2008
3/26/2013
3/23/2028
Granted
Papillomavirus L2 N-Terminal Peptides for the Induction of Broadly Cross-Neutralizing Antibodies
CON: Continuation
United States
13/772,893
9,388,221
2/21/2013
7/12/2016
2/1/2026
Granted
Direct Link:
https://jhu.technologypublisher.com/technology/16367
Inventors:
Category(s):
Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology > Cervical Cancer, Clinical and Disease Specializations > Women's Health, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Vaccines, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities, Clinical and Disease Specializations > Infectious Diseases > Human Papillomavirus (HPV),
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For Information, Contact:
Vera Sampels
vsampel2@jhu.edu
410-614-0300
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