CHK2 KO Lines for Drug Discovery

Case ID:

C04655

C04655: CHK2 KO Lines for Drug Discovery
Technical Details:
Chk2 protein kinase gene knockouts of the human colorectal carcinoma cell line, HCT116. Details are described in the paper by Jallepalli et al., 2003 (see below).
Looking for Partners:
The cell lines described in this invention can be used in screens for novel molecules that target the CHK2 pathway in human cancer cells or to confirm the specificity of drugs discovered through other approaches. Such drugs can potentially be used as chemotherapeutic or chemopreventive agents.

Direct Link:

https://jhu.technologypublisher.com/technology/16382

Inventors:

Category(s):

Clinical and Disease Specializations, Clinical and Disease Specializations > Gastroenterology, Clinical and Disease Specializations > Oncology > Colorectal Cancer, Technology Classifications > Research Tools > Assays, Technology Classifications > Research Tools > Human Cell Lines, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools,

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For Information, Contact:

Jeanine Pennington

jpennin5@jhmi.edu

410-614-0300

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