DEC1 KO Lines for Drug Discovery

Case ID:

C04656

Disclosure Date:

3/11/2005

C04656: DEC1 KO Lines for Drug Discovery
Technical Details:
Deleted in esophageal cancer 1 (DEC1) gene knockouts of the human keratinocyte cell line, HaCaT. Details are described in the paper by Zawel et al., 2002
Looking for Partners:
The cell lines described in this invention can be used in screens for novel molecules that target the TGF-Beta pathway in human cancer cells or to confirm the specificity of drugs discovered through other approaches. Such drugs can potentially be used as chemotherapeutic or chemopreventive agents.

Direct Link:

https://jhu.technologypublisher.com/technology/16383

Inventors:

Category(s):

Clinical and Disease Specializations, Clinical and Disease Specializations > Ear, Nose & Throat, Clinical and Disease Specializations > Oncology > Esophageal Cancer, Technology Classifications > Research Tools > Assays, Technology Classifications > Research Tools > Human Cell Lines, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools,

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For Information, Contact:

Jeanine Pennington

jpennin5@jhmi.edu

410-614-0300

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