C04656: DEC1 KO Lines for Drug Discovery
Technical Details:
Deleted in esophageal cancer 1 (DEC1) gene knockouts of the human keratinocyte cell line, HaCaT. Details are described in the paper by Zawel et al., 2002
Looking for Partners:
The cell lines described in this invention can be used in screens for novel molecules that target the TGF-Beta pathway in human cancer cells or to confirm the specificity of drugs discovered through other approaches. Such drugs can potentially be used as chemotherapeutic or chemopreventive agents.
