XIAP KO Lines for Drug Discovery

Case ID:

C04657

Disclosure Date:

3/11/2005

C04657: XIAP KO Lines for Drug Discovery
Technical Details:
X-linked inhibitor of apoptosis protein (XIAP) gene knockouts of human colon cancer cell lines. Details are described in the paper by Cummins et al., 2004 (see below).
Looking for Partners:
The cell lines described in this invention can be used in screens for novel molecules that target the mitochondrial death pathway in human cancer cells or to confirm the specificity of drugs discovered through other approaches. Such drugs can potentially be used as chemotherapeutic or chemopreventive agents.

Direct Link:

https://jhu.technologypublisher.com/technology/16384

Inventors:

Category(s):

Clinical and Disease Specializations, Clinical and Disease Specializations > Gastroenterology, Clinical and Disease Specializations > Oncology > Colorectal Cancer, Technology Classifications > Research Tools > Assays, Technology Classifications > Research Tools > Human Cell Lines, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools,

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For Information, Contact:

Jeanine Pennington

jpennin5@jhmi.edu

410-614-0300

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