HAUSP KO Lines for Drug Discovery

Case ID:

C04658

Disclosure Date:

3/11/2005

C04658: HAUSP KO Lines for Drug Discovery
Technical Details:
HAUSP (also known as USP7) deubiquitinase gene knockouts of the human colorectal carcinoma cell line, HCT116. Details are described in the paper by Cummins et al., 2004a (see below)
Looking for Partners:
The cell lines described in this invention can be used in screens for novel molecules that target the p53 pathway in human cancer cells or to confirm the specificity of p53-targeted drugs discovered through other approaches.

Direct Link:

https://jhu.technologypublisher.com/technology/16385

Inventors:

Category(s):

Clinical and Disease Specializations, Clinical and Disease Specializations > Gastroenterology, Clinical and Disease Specializations > Oncology > Colorectal Cancer, Technology Classifications > Research Tools > Assays, Technology Classifications > Research Tools > Human Cell Lines, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools,

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For Information, Contact:

Jeanine Pennington

jpennin5@jhmi.edu

410-614-0300

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