Mutational Analysis of the Serine-threonine Kinome in Colorectal Cancers

Case ID:

C04724

Disclosure Date:

5/16/2005

C04724: Mutational Analysis of the Serine-threonine Kinome in Colorectal Cancers
Technical Details:
The invention describes novel mutations in serine-threonine kinase genes within the Phosphatidylinositol-3-OH Kinase (PI(3)K) pathway in patients with colorectal cancer. Details are described in the paper by Parsons et al., 2005 (see below).
Looking for Partners:
The discovery of novel mutations in PI(3)K pathway genes provide a basis for the development of new therapeutic and diagnostic approaches for such patients.
Publications/Associated Cases:
Issued US Patent 9,580,750; Parsons D et al. (2005) “Colorectal cancer: mutations in a signaling pathway”. Nature. 436:792

Patent Information:

Title	App Type	Country	Serial No.	Patent No.	File Date	Issued Date	Expire Date	Patent Status
PI3K Pathway Mutations in Cancer	PCT: Patent Cooperation Treaty	United States	11/920,860	9,580,750	11/12/2010	2/28/2017	2/28/2032	Granted

Direct Link:

https://jhu.technologypublisher.com/technology/16401

Inventors:

Category(s):

Clinical and Disease Specializations, Clinical and Disease Specializations > Gastroenterology, Clinical and Disease Specializations > Oncology > Colorectal Cancer, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology,

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For Information, Contact:

Jeanine Pennington

jpennin5@jhmi.edu

410-614-0300

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